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In ''The Heart Broke In'', James Meek manages to combine some big and serious issues into a compellingly readable and entertaining moral thriller. At the centre of the book are two siblings who are very different. Ritchie is a former rock star, now working in the world of reality television producing a game show about teenage pop bands while his younger sister, Bec, is a devoted scientist working on a cure for malaria. On the one hand it's a story of family dynamics, but it's also a thoughtful and well constructed tale of morality and judgement. Setting science against religion it asks very modern day questions about who is the guardian of morality in today's world and who, if anyone, has the right to judge others' behaviour.